Open data

Download

Association catalog, UHGG reference genomes, gene annotations and CDS sequences for offline analysis.

Primary release

Main catalog

SNV-MWAS Catalog (TSV)

Complete association results including SNV coordinates, alleles, effect sizes, significance flags and gene annotations.

Format TSV · Size ~863 MB · Records 1,389,120
Download TSV Custom subset via Explore
References

Reference data

Species information

Taxonomy and metadata for microorganisms in the catalog.

TSV · 909 species
Download

Reference genomes

UHGG reference genome sequences for 909 species.

FASTA.gz · ~755 MB · 909 species
Download
Annotations

Gene & SNV annotation

Gene annotations (GFF3)

Gene coordinates and functional annotations.

GFF3.gz · ~132 MB · 516,851 entries
Download

Detailed gene annotation (UniProt)

Protein information mapped to UniProt clusters.

TSV.gz · ~1.2 GB · 4,679,748 proteins
Download

SNV impact annotation

Predicted functional consequences for coding and non-coding SNVs.

TSV.gz · ~343 MB · 1,398,210 SNVs
Download

CDS sequences

Coding DNA sequences for protein-coding genes in the reference set.

FASTA.gz · ~730 MB · 2,370,420 CDS
Download

Usage tips

  • Use Explore to search, filter and export associations.
  • Large archives (>100 MB) are compressed; a download manager helps for multi-GB files.
  • Index local TSV copies with DuckDB/SQLite for fast offline queries.
  • Gene sequence bundles from Explore may be unavailable for non-coding regions — use the genome/GFF downloads instead.

Citation

Daoming Wang, et al. Microbiome-wide PheWAS links gut microbial SNVs to human health and exposures, 25 September 2024, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-5063726/v1]
Data is provided for research purposes. Respect source-study terms of use; contact us for commercial licensing.